Approccio globale alla Prevenzione e alla Cura del Dolore del Neonato, Bambino e Adolescente
A breve saranno aperte le iscrizioni al Corso di Perfezionamento in ‘Approccio globale alla Prevenzione e alla Cura del Dolore del Neonato, Bambino e Adolescente’, nato per offrire ai Pediatri un programma educativo di un grande valore scientifico e morale, e dal quale si potranno ottenere 9 crediti ECM. Il corso si terrà a Siena dal 16 al 19 marzo 2023
Prof.ssa Anna Maria Aloisi
Prof. Carlo Valerio Bellieni
Partecipa alla spedizione Annamaria Aloisi, Università di Siena, Biomedicine and Nutrition Network of Research, Biomedicina e Nutrizione
About The Health & Nutrition Summit
Food and Nutrition
ConferenceSeries LLC invite all the speakers, dietitian, nutritionists, nutrition science researchers, experts, experimenters, officials, moderators, researchers, exhibitors and students to join the 4th International conference on food and nutrition which will be conducted on April 06-07, 2023 at Madrid, Spain. The event welcomes all researchers to take part in this conference on food and nutrition. This conference is to “Gain your powers and strengths with the knowledge on food and nutrition to achieve your goals and also through this, we can protect our planet”.
Valeria Bachiocco¹, Marco Cappa², Anna Petroni¹³, Ettore Salsano⁴, Carla Bizzarri², Ilaria Ceccarelli¹, Gabriele Cevenini⁵, Viviana Pensato⁴ and Anna Maria Aloisi¹³
1 University of Siena, Department of Medicine, Surgery and Neuroscience, Siena, Italy;
2 Bambino Gesù Children’s Hospital, IRCCS Rome, Italy
3 Biomedicine and Nutrition Research Network, Via Paracelso 1, 20129 Milan, Italy
4 Neurological Institute Carlo Besta, IRCCS Milan, Italy
5 University of Siena, Department of Medical Biotechnology, Siena, Italy
X-linked adrenoleukodystrophy (ALD) is a metabolic disorder in which very long chain fatty acids (VLCFAs) are accumulated in the nervous system and adrenal cortex, impairing their functions. Three main variants are described in males: adrenomyeloneuropathy (AMN), a cerebral form (cALD or cAMN) and Addison disease only (AD), while for females no classification is used. Chronic pain occurrence and sensory phenotype profile were assessed in 30 patients (20 males: 10 AMN, 1 cAMN, 1 cALD, 8 AD, and 10 females). A set of instruments assessed the intensity, quality and extent of pain, while a battery of Quantitative Sensory Testing (QST) procedures examined the functional status of Ab and Ad fibers. Principal component analysis and hierarchical clustering with sensory responses input were used to identify distinct clusters.
Nearly half of the subjects reported pain, with high prevalence in females and male AMN patients. No sex differences in pain dimensions were found. The sensory responses were heterogeneous, differing among the clinical variants and between genders. Male AMN/cAMN/cALD patients showed the worst impairment. Ab and Ad fibers were affected in males and females, but Ab fibers appeared undamaged in females when tactile sensitivity was tested. Abnormal responses were localized in the lower body district, according to the dying-back pattern of the neuropathy. Cluster analysis showed discrete clusters for each function examined, with well-interpretable sensory and clinical phenotypes. The study of pain and of the sensory profile appears to indicate a difference in the mechanisms underlying the AMN/cAMN /cALD and AD clinical forms and in the treatment of the respective generated pains.
Obiettivi del Master
Il corso si rivolge ai laureati di area sanitaria coinvolti nella gestione del paziente oncologico in ambito clinico e sul territorio ed in particolare ai laureati in Dietistica che vogliano accrescere conoscenze specifiche attraverso una formazione a carattere interdisciplinare per conseguire i seguenti obiettivi:
La pandemia da Corona virus sta colpendo tutti noi.
Il nostro impegno è dedicato alla salute, stiamo continuando la nostra ricerca anche nel campo delle strategie antivirali.
La ricerca sui disturbi neurodegenerativi è sempre in corso.
La nostra prossima pubblicazione è intitolata:
Pain study in X-linked adrenoleukodystrophy in males and females
Valeria Bachiocco, Marco Cappa, Anna Petroni, Ettore Salsano, Carla Bizzarri, Ilaria Ceccarelli, Gabriele Cevenini, Viviana Pensato and Anna Maria Aloisi
Nutritional and molecular approach to metabolic/neurodegenerative disorders
Anna Petroni, Rita Paroni and Anna Maria Aloisi
Biomedicine and Nutrition Research Network, Via Paracelso 1, 20129 Milan, Italy
Verrà presentato al congresso: Nutrition 2020